New glaucoma therapy developed in the United States

Release date: 2007-08-07

A groundbreaking new treatment for glaucoma has been developed in the United States by a team at Iowa State University. The researchers discovered that transplanting specially modified bone marrow stem cells can effectively treat the condition. This innovative approach is now being tested on dogs, as their eyes share a high degree of similarity with human eyes, making them an ideal model for future clinical trials in humans. The study suggests that this therapy could one day offer a long-term solution for patients suffering from glaucoma. Previously, the research team found that animals affected by glaucoma naturally produce more neurotrophins—substances that help protect the eyes from damage. Inspired by this natural defense mechanism, the scientists extracted bone marrow stem cells from the mice and genetically enhanced them to generate these protective neurotrophins. The modified cells were then injected into the eyes of the affected mice, resulting in a significant improvement in their vision. One of the key advantages of this treatment is that the transplanted cells can continue producing beneficial nutrients for several years. Additionally, since the stem cells are taken from the patient’s own body, the risk of immune rejection is greatly reduced. This makes the therapy both safer and more sustainable compared to traditional treatments. With further research and testing, this promising method may soon become a viable option for treating glaucoma in humans, offering hope to millions of people worldwide who suffer from this sight-threatening disease.

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