Researchers at the University of Oregon recently reported that the use of microfluidic chips to read parasitic worm electrophysiological signals can be used to screen for potential anti-parasitic helminth compounds, a result that has promised to speed up research on new drugs for parasitic worms.
The University of Oregon study was conducted primarily on ground-borne worms. Soil-borne worms include aphids, hookworms, whipworms, aphids, etc. These parasitic worms do not require an intermediate host, and their eggs or larvae can infect humans directly from the outside to the infected stage. Many people have been infected with more than one kind of soil-borne worms. They live and lay eggs in the human intestines, which may lead to diseases such as anemia and malnutrition, which cause serious damage to human health, especially children's development.
University of Oregon biologist Janis Wicks and colleagues have previously developed a microfluidic chip that can be used to study the central nervous system of tiny organisms. Their use of this microfluidic chip for C. elegans studies has shown that this nematode has an electrophysiological signal when it has a rhythmic contraction. Inspired by this, researchers believe that this microfluidic chip is expected to be used for anti-parasitic helminth drug research.
The microfluidic chip refers to the integration of basic operating units of biological, chemical or medical laboratories on a nanometer-scale microchip to realize all the functions of the laboratory.
The researchers fed parasitic worms placed on microfluidic chips, causing their pharynx to contract rhythm. The microfluidic chip captures the electrophysiological signals between the worm's neurons and the muscles, thereby monitoring the pharyngeal movement of the worm. The researchers then injected compounds into the device that could damage the pharyngeal movements of the worms, observing which compounds actually destroyed the pharyngeal contractions of the worms and eventually starved them. On this microfluidic chip, researchers can screen for potentially anti-parasitic helminth compounds on eight living parasitic worms at a time.
Fruit And Vegetable Cleaning Line
It adopts bubble rolling ,scrubbing and spraying technology to maximize material cleaning.
The cleaning machine uses high pressure bubble water to clean,effectively separate the surface attachments of the cleaned objects, simulate the basic action of manual cleaning , and avoid touching ,knocking and scratching in manual cleaning .The speed of the conveyor belt is adjustable, and the user can arbitrarily set according to different cleaning contents.Cleaning capacity is large ,cleaning rate is high and material is not damaged.
Vegetable Washing Machine Cleaner,Vegetable Cleaning Machine,Fruit Washing Machine,Fruit Cleaning Line
Zhucheng Tongxi Commercial And Trade Co.,Ltd. , https://www.blackgarlicgroup.com