Japanese scientists have succeeded in cultivating pups by combining two maternal oocytes, and for the first time they have achieved mammalian parthenogenetic breeding, thereby breaking the inheritance laws of mammalian reproduction that must depend on both male and female. Monosex reproduction is common in the reproduction of plants, fish, frogs, and insects, but it is difficult to achieve in mammals. Scientists at Tokyo Agricultural University used this technique to develop a mother that lacks the H19 and Igf2 genes, which control the development of the fetus. Experts believe that this study clearly proves that "genetic markers" are the reasons for the inhibition of parthenogenesis. This technique helps researchers analyze the genetic modification process to understand how this process controls the development of the embryo.
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